A local anaestheitic is injected, and a needle is
inserted into the muscle. A small piece of tissue remains in the
needle when it is removed. Sometimes, a small incision in the skin
may be needed to get a sample of the muscle.
The area may sting or burn when the anaesthetic is
injected. Pulling or tugging sensations may be felt, but there should
be no pain. When the anaesthetic wears off, the area may be sore
for about 1 week.
A muscle biopsy can reveal conditions such as:
atrophy (loss of muscle mass)
necrosis (tissue death) of muscle fibers
inflammation of the muscle
myopathic changes (destruction of the muscle)
muscular dystrophy, indicated by antibody staining of the
muscle biopsy specimen that can show deficient dystrophin